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Serum Neurofilament Light Chain in Multiple Sclerosis: Superiority of Age- and BMI-Corrected Z Scores/Percentiles Over Absolute Cutoff Values for Prediction of Treatment Response

delete2025-08-03
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M
Maximilian Einsiedler
A
Aleksandra Maleska Maceski
S
Sofia Sandgren
J
Johanna Oechtering
S
Sabine Schädelin
L
Lisa Hofer
A
Amar Zadic
J
Juan Gómez
L
Lester Melie‐García
A
Alessandro Cagol
R
Riccardo Galbusera
S
Sebastian Finkener
P
Patrice H. Lalive
M
Marjolaine Uginet
S
Stefanie Müller
C
Caroline Pot
A
Amandine Mathias
R
Renaud Du Pasquier
R
Robert Hoepner
A
Andrew Chan
G
Giulio Disanto
C
Chiara Zecca
M
Marcus D’Souza
L
Lars G. Hemkens
T
Tobias Derfuss
Ö
Özgür Yaldizli
P
Patrick Roth
C
Claudio Gobbi
D
David Brassat
B
Björn Tackenberg
H
Henrik Zetterberg
T
Tjalf Ziemssen
H
Heinz Wiendl
K
Klaus Berger
M
Marco Hermesdorf
F
Fredrik Piehl
L
Ludwig Kappos
C
Cristina Granziera
A
Ahmed Abdelhak
L
Leppert, David
E
Eline A.J. Willemse
P
Pascal Benkert *
J
Jens Kühle *
S
Swiss Multiple Sclerosis Cohort Study (SMSC)
DOI:10.1002/acn3.70149delete
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Abstract

Abstract

En 中文
Prognostication of disease course and prediction of treatment response in multiple sclerosis is an unmet need. We compared the performance of serum neurofilament light chain Z scores (age- and BMI-adjusted) with absolute concentrations for the prediction of response to disease-modifying therapy.
Keywords:
multiple sclerosis
neurofilament
prediction
Z scores
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Journal

Annals of Clinical and Translational Neurology cover
Annals of Clinical and Translational Neurology
IF:
3.9
Papers:
2.6K
Citations:
7.4K

Organization

N
neurocenter of southern switzerland
Scholars:
30
Papers: 15
Citations: 0
P
philipps-university
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11
Papers: 7
Citations: 0
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university of california
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Papers: 8.0K
Citations: 10
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university of gothenburg
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Papers: 2.3W
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cantonal hospital aarau
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70
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Citations: 0
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novartis pharma ag, basel, switzerland
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38
Papers: 15
Citations: 0
U
University of Münster
Scholars:
832
Papers: 349
Citations: 1
C
cantonal hospital st gallen
Scholars:
39
Papers: 22
Citations: 0
T
Technical University of Dresden
Scholars:
85
Papers: 51
Citations: 1
U
University Hospital Zurich and University of Zurich
Scholars:
95
Papers: 26
Citations: 0
U
university hospital and university of basel
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50
Papers: 16
Citations: 0
K
Karolinska Institutet
Scholars:
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Papers: 4.8W
Citations: 7.1W
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university hospital freiburg
Scholars:
39
Papers: 29
Citations: 0
U
University of Bern
Scholars:
3.9W
Papers: 3.1W
Citations: 4.8W
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