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Sesame extract restores iron homeostasis and exercise endurance in anemic rats: Insights into gut microbial remodeling and hepcidin suppression
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DOI：10.1016/j.jff.2026.107400.png)
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Abstract
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• Sesame and iron synergy boosts endurance in anemic rats. • Combined therapy restores hemoglobin and red blood cell counts. • Sesame extract aids absorption by downregulating hepcidin. • Supplements reverse dysbiosis and increase microbial diversity. • Lactobacillus and Clostridium correlate with fatigue resistance.
Keywords:
Sesame extract
Ferrous sulfate
Hepcidin
iron deficiency
Gut microbiota
Endurance performance
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