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Setdb1 represses anti-tumor immunity and tertiary lymphoid structures in hepatocellular carcinoma
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DOI：10.1016/j.jhep.2026.07.007.png)
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Abstract
En 中文
• Setdb1 depletion induces mature TLSs in HCC. • Setdb1 knockout and immunotherapy synergistically repress HCC. • Setdb1 depletion induces TLSs through cGas pathway. • Cxcl12 is downstream of cGas pathway and required for TLS formation.
Journal
IF:
33
Papers:
3.2W
Citations:
6.5W
Organization
Cited Papers