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Sevoflurane and propofol decrease intraocular pressure equally during non-ophthalmic surgery and recovery
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DOI：10.1093/bja/aef249.png)
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Abstract
En 中文
Background. To provide good control of intraocular pressure (IOP) during anaesthesia and surgery, we conducted a study comparing the effects on IOP during maintenance and recovery of sevoflurane vs propofol anaesthesia in 33 patients (ASA I-II) undergoing elective nonophthalmic surgery. Methods. Anaesthesia was induced with propofol 2 mg kg(-1), fentanyl 2 mug kg(-1) and vecuronium 0.1 mg kg(-1). Patients were allocated randomly to receive either propofol 4-8 mg kg(-1) h(-1) (group P; n= 16) or 1.5-2.5 vol% sevoflurane (group S; n= 17) for maintenance of anaesthesia. Fentanyl 2-4 mug kg(-1) was added if necessary. The lungs were ventilated with 50% air in oxygen. Blood pressure, heart rate, oxygen saturation and end-tidal carbon dioxide were measured before and throughout anaesthesia and in the recovery room. IOP was determined with applanation tonometry (Perkins) by one ophthalmologist blinded to the anaesthetic technique. Results. There was a significant decrease in IOP after induction and during maintenance of anaesthesia in both groups. No significant differences in IOP between the two groups was found. Conclusion. Sevoflurane maintains the IOP at an equally reduced level compared with propofol.
Keywords:
anaesthetics i.v., propofol
anaesthetics volatile, sevoflurane
analgesics opioid, fentanyl
eye, intraocular pressure
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