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Sex differences in impact of daily and chronic psychological stressors on diurnal cortisol level
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DOI：10.1016/j.pbb.2026.174165.png)
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Abstract
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• Chronic stress contributes to multiple mental disorders. • It is unknown if chronic stress affects cortisol level in men and women differently. • Both daily and chronic stressors were associated with increased morning cortisol level. • Chronic stress was associated with lower cortisol level in the afternoon. • Associations between cortisol and chronic stressors were context and sex specific.
Keywords:
Stress
Hypothalamic-pituitary-adrenal axis
Cortisol
Depression
Anxiety
Mental health
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