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Signalling for secretion
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DOI：10.1038/ncb0905-851.png)
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Abstract
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How proteins exit the Golgi apparatus on their way to the plasma membrane is poorly understood. Protein kinase D ( PKD) is known to regulate this process, but its downstream targets have remained elusive. New work now identifies a previously known player in Golgi dynamics - phosphatidylinositol 4- kinase III beta - as a physiological PKD substrate.
Keywords:
PROTEIN-KINASE-D
TRANS-GOLGI NETWORK
CELL-SURFACE
MEMBRANE
RECRUITMENT
FISSION
COMPLEX
ROLES
ARF
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