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Similar destabilization of neural dynamics under different general anesthetics

delete2026-03-17
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OA
AI
A
Adam Eisen
A
Alexandra Bardon
J
J. J. Ballesteros
A
André M. Bastos
J
Jacob Donoghue
M
Meredith Mahnke
S
Scott L. Brincat
J
Jefferson E. Roy
Y
Yumiko Ishizawa
E
Emery N. Brown
I
Ila R. Fiete *
E
Earl K. Miller *
DOI:10.1016/j.celrep.2026.117048delete
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Abstract

Abstract

En 中文
• Propofol, ketamine, and dexmedetomidine similarly destabilize cortical dynamics • Neural activity exhibits slower recovery from sensory perturbation during unconsciousness • Destabilization accounts for low-frequency oscillations during anesthesia
Keywords:
anesthesia
consciousness
dynamical systems
dynamic stability
propofol
ketamine
dexmedetomidine
neural oscillations
neural dynamics
Koopman operators
CP: neuroscience
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Journal

Cell Reports cover
Cell Reports
IF:
6.9
Papers:
1.7W
Citations:
10.2W

Organization

H
Harvard University
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26.2W
Papers: 21.9W
Citations: 28.7W
R
Ruhr-Universität Bochum
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295
Papers: 116
Citations: 0
V
vanderbilt university
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5.0W
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Citations: 59
M
massachusetts institute of technology
Scholars:
3.4K
Papers: 1.3K
Citations: 0
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