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Single-Cell and Multiomics Characterization of p21 in Cancer Progression and Therapeutic Sensitivity

delete2026-07-06
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OA
AI
W
Wenyang Zhang
Q
Qinglong Ma
H
Honghui Zhao
W
Wenrun Li
Z
Zidong Feng
L
Linghui Zhong
Y
Yaru Ren
L
Lin Chang
李永红 (Yonghong Li) *
石磊 (Lei Shi) *
DOI:10.1155/humu/5598948delete
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Abstract

Abstract

En 中文
CDKN1A (encoding p21) is a canonical regulator of cell cycle arrest and genomic stability. However, its functional spectrum within the tumor microenvironment (TME), especially at single-cell resolution, remains insufficiently defined.
Keywords:
CDKN1A/p21
cell cycle
prognostic biomarker
scRNA-seq
tumor microenvironment
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Human Mutation cover
Human Mutation
IF:
3.7
Papers:
5.1K
Citations:
1.3W

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L
Lanzhou University
Scholars:
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Papers: 2.8K
Citations: 3.8W
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