Single-cell RNA sequencing provides further insights into the immunostimulatory action of freeze-dried Lactiplantibacillus plantarum on Penaeus vannamei shrimp

John Paul Matthew D. Guzman

doi:10.1016/j.fsi.2026.111643

Single-cell RNA sequencing provides further insights into the immunostimulatory action of freeze-dried Lactiplantibacillus plantarum on Penaeus vannamei shrimp

2026-08-11

0

PRE

AI

J

John Paul Matthew D. Guzman

H

Hiroki Kusaka

C

Claudio Gargano

M

Ma Ramela Angela Bermeo-Capunong

M

Mikio Aoki

H

Hiroshi Kuwahara

H

Hidehiro Kondo

K

Keiichiro Koiwai

I

Ikuo Hırono *

DOI：10.1016/j.fsi.2026.111643

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Abstract

En 中文

• Cell atlas of Penaeus vannamei gills was established through single-cell RNA seq • Immunity and metabolism genes were identified as DEGs at global- and cluster levels • Immunostimulation by freeze-dried LAB involves shifts in cell population • Cell population dynamics contribute to overall transcriptomic changes

Keywords:

Cell population dynamics

Drop-seq

Feed supplement

Lactic acid bacteria

Single-cell RNA sequencing provides further insights into the immunostimulatory action of freeze-dried Lactiplantibacillus plantarum on Penaeus vannamei shrimp

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