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Single-cell transcriptomic analysis reveals the T lymphocyte microenvironment and identifies HOPX as a hub gene in membranous nephropathy

delete2026-06-17
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PRE
AI
Y
Yao Li
Y
Yaoyao Wang
Y
Yanjiao Hou
Q
Qing Zheng
W
Wei Zhang *
X
Xiancong Yang *
DOI:10.1016/j.gene.2026.150273delete
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Abstract

Abstract

En 中文
• Single-cell transcriptomic atlas of T/NK cells in membranous nephropathy. • T/NK cells show expansion, exhaustion, and metabolic remodeling in non-remission. • HOPX identified as a hub gene by multi-algorithm machine learning. • HOPX may serve as an adjunctive biomarker for membranous nephropathy.

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the affiliated hospital of qingdao university
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fujian medical university
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yantai yuhuangding hospital
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shandong university
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qingdao university
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