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Single-cell transcriptomics identifies potential roles of CCL2-mediated macrophage-endothelial cell interactions in endothelial apoptosis of varicose veins
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DOI：10.1016/j.gene.2026.150279.png)
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Abstract
En 中文
• Applying single-cell sequencing technology to varicose veins is innovative. • All the single-cell data in this study are original. • Single-cell transcriptomics uncovers altered cellular heterogeneity and the key CCL2-ACKR1 axis in varicose veins. • This study unveils cell-type-specific heterogeneity and CCL2-mediated macrophage-endothelial interactions that may relate to endothelial apoptosis in varicose veins.
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