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Single-step CRISPR detection of Mycobacterium tuberculosis based on a boat-shaped lateral flow strip device

delete2026-08-10
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PRE
AI
H
Haoyuan Wu
Y
Yi Chen
Z
Zhu Wang
Z
Zhangbo Dong
Y
Yaoyao Li
T
Tingting Ye
X
Xia Zhang
D
Dong Shi
L
Ling Xu
S
Shijia Ding
G
Guozhen Tian *
R
Rui Chen *
W
Wei Yang *
DOI：10.1016/j.snb.2026.140675delete
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Abstract

Abstract

En 中文
• A CRISPR-TB platform integrating RPA, CRISPR-Cas13a and LFSA is constructed for ultrasensitive visual detection of MTB. • A novel boat-shaped integrated LFSA device realizes naked-eye MTB detection with a limit of 20 copies/μL. • Lyophilized reagents improve system portability and permit accurate on-site MTB testing in resource-limited settings without sophisticated instruments.

Journal

Sensors and Actuators B-Chemical cover
Sensors and Actuators B-Chemical
IF:
7.7
Papers:
3.3W
Citations:
12.6W

Organization

C
Chongqing Medical University
Scholars:
5.9K
Papers: 1.5K
Citations: 2.8W
Z
zhejiang provincial people's hospital bijie hospital
Scholars:
6
Papers: 2
Citations: 0
H
hainan medical university
Scholars:
6.6K
Papers: 3.6K
Citations: 10
H
Hainan Women and Children's Medical Center
Scholars:
39
Papers: 21
Citations: 0
H
hangzhou medical college
Scholars:
1.3K
Papers: 411
Citations: 0
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