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Skin safety of 233 nm far UV-C ex vivo and in vivo – Pilot study for evaluating different populations and multiple exposures
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DOI：10.1016/j.jphotobiol.2025.113262.png)
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Abstract
En 中文
• Single 233 nm far UV-C exposure causes minimal DNA damage, all within safe limits. • Elderly and dark-skinned individuals show higher residual damage 24 h after exposure. • No changes for p53, langerin and antioxidant capacity for all groups and time points. • DNA repair begins within 24 h, with nearly all damage repaired after 7 days. • Repeated 233 nm far UV-C exposure leads to CPD accumulation.
Keywords:
Germicidal UV
DNA damage
Age dependence
Melanin dependence
Resistant pathogens
DNA repair mechanisms
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