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Small-angle scattering and 3D structure interpretation
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DOI：10.1016/j.sbi.2016.05.003.png)
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Abstract
En 中文
This review focuses on advances in the application of solution small-angle scattering (SAS) in structural analysis of biomolecules and the complexes they form. Examples highlighted illustrate the unique contribution of SAS, using both X-rays and neutrons, in hybrid or integrative modelling methods. The increased information content when neutron scattering with contrast variation is used is a particular focus. Finally, progress toward an agreed reporting framework, the development of open data and model archives, and the importance of these initiatives is covered.
Keywords:
X-RAY-SCATTERING
NEUTRON-SCATTERING
CONTRAST VARIATION
SAXS
NMR
PROTEINS
COMPLEX
CONFORMATIONS
COMPUTATION
BIOGENESIS
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