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Small RNAs and Beyond: Regulatory Architectures of Bacterial Endosymbionts in Insect Hosts
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DOI：10.1016/j.cois.2026.101558.png)
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Abstract
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• Insect symbionts with highly reduced genomes lack canonical protein-based transcriptional regulatory machinery. • Small RNAs (sRNAs) represent an independent mechanism for post-transcriptional control in streamlined symbiont genomes. • Evidence for sRNA-mediated regulation has emerged across multiple insect–bacterial symbioses. • Integrative multi-omic approaches can resolve how gene regulation operates in these reduced systems.
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