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Smart exosomes: multimodal engineering strategies for logic-gated and stimuli-responsive precision theranostics

delete2026-05-07
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PRE
AI
Y
Yuhe Hu
X
Xue Yang
F
Fuxing Shu
L
Leilei Jin
S
Surendra Sarsaiya
S
Shiqing Han *
J
Jishuang Chen *
DOI:10.1016/j.ijpharm.2026.126846delete
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Abstract

Abstract

En 中文
Exosomes are endogenous extracellular vesicles with exceptional biocompatibility and intrinsic targeting potential, yet their clinical translation is limited by functional heterogeneity, insufficient controllability, and lack of spatiotemporal precision. While numerous engineering strategies have been developed, most remain confined to single-function enhancement and fail to achieve coordinated, programmable therapeutic control.
Keywords:
Exosomes
Theranostics
Engineering strategies
Stimuli-responsive
Precision medicine

Journal

International Journal of Pharmaceutics cover
International Journal of Pharmaceutics
IF:
5.2
Papers:
2.2W
Citations:
6.7W

Organization

Z
zunyi medical university
Scholars:
3.2K
Papers: 884
Citations: 110
N
Nanjing Tech University
Scholars:
3.5W
Papers: 2.2W
Citations: 3.9W
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