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SnRK2 and MLKs Orchestrate FREE1 Nuclear Retention through Phosphorylation to Regulate ABA Signaling in Arabidopsis
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DOI：10.1016/j.plantsci.2026.113281.png)
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Abstract
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• The work uncovers a novel, hierarchical regulatory layer in ABA signaling where SnRK2 and MLK kinases synergistically but independently control FREE1, with MLK-mediated phosphorylation playing a dominant role in regulating FREE1's nuclear function and ABA response. • Our findings unveil a novel regulatory layer of ABA signaling and establish a framework for understanding the synergistic action of SnRK2 and MLK kinases.
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