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Sodium Oxybate: Practical Considerations and Patient Perspectives

delete2025-03-20
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OA
AI
M
Maggie Lavender *
C
Cécile Martin
D
Diana C. Anderson
DOI:10.1007/s40263-024-01144-6delete
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Abstract

Abstract

En 中文
Narcolepsy is a rare, chronic sleep disorder with significant impacts on the quality of life of people affected by the disorder. People with narcolepsy (PWN) are a diverse patient population with evolving symptoms, comorbidities, and perspectives. As PWN have varying needs, clinicians should consider a more personalized approach to therapy, including active participation of PWN in their care and shared decision-making between patient and clinician to achieve optimal outcomes. In this review, we discuss the various characteristics and challenges of PWN, present illustrative clinical case scenarios of PWN, provide clinicians with a proposed framework to best address therapy for PWN, and demystify concerns with sodium oxybate.
Keywords:
DISRUPTED NIGHTTIME SLEEP
NARCOLEPSY-CATAPLEXY
NOCTURNAL SLEEP
DOUBLE-BLIND
MANAGEMENT
FORMULATION
DEFICITS
PLACEBO
BURDEN
FT218

Journal

CNS Drugs cover
CNS Drugs
IF:
7.4
Papers:
2.5K
Citations:
7.0K

Organization

No organization information available
Cited Papers

Cited Papers

0579 Long-Term Safety of Once-Nightly Oxybate for Narcolepsy: RESTORE Study Interim Analysis of Data
err2023-05-29
err0
errOAAI
errThomas Stern; Asim Roy; Colin Shapiro; John Harsh; Akinyemi Ajayi; Sally Ibrahim; Jordan Dubow; Jennifer Gudeman
errShare
errSave
A pilot study on the effects of sodium oxybate on sleep architecture and daytime alertness in narcolepsy
errSLEEP
IF4.9
err2004-10-01
err141
errOAAI
errMamelak, M; Black, J; Montplaisir, J; Ristanovic, R
errShare
errSave
Short-Term Triazolam Use Improves Nocturnal Sleep of Narcoleptics
err1992-05-01
err0
errOAAI
errMichael J. Thorpy; Michael Snyder; Flavio S. Aloe; Philip S. Ledereich; Kenneth E. Starz
errShare
errSave
Narcolepsy with cataplexy
errLANCET
IF88.5
err2007-02-01
err577
PREAI
errDauvilliers, Yves; Amulf, Isabelle; Mignot, Emmanuel
errShare
errSave
Shared Decision Making: A Model for Clinical Practice
err2012-05-23
err2.8K
errOAAI
errElwyn, Glyn; Frosch, Dominick; Thomson, Richard; Joseph-Williams, Natalie; Lloyd, Amy; Kinnersley, Paul; Cording, Emma; Tomson, Dave; Dodd, Carole; Rollnick, Stephen; Edwards, Adrian; Barry, Michael
errShare
errSave
The impact of accommodating client preference in psychotherapy: A meta‐analysis
err2018-08-08
err0
PREAI
errJoshua K. Swift; Jennifer L. Callahan; Mick Cooper; Susannah R. Parkin
errShare
errSave
How to interpret the results of a sleep study
err2014-11-24
err0
errOAAI
errDeepak Shrivastava; Syung Jung; Mohsen Saadat; Roopa Sirohi; Keri Crewson
errShare
errSave
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