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Spatially resolved transcriptomics in immersive environments

delete2022-01-10
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OA
AI
B
Bienroth, Denis
H
Hieu T. Nim
D
Dimitar Garkov
K
Karsten Klein
J
Jaeger-Honz, Sabrina
M
Mirana Ramialison *
S
Schreiber, Falk *
DOI:10.1186/s42492-021-00098-6delete
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Abstract

Abstract

En 中文
Spatially resolved transcriptomics is an emerging class of high-throughput technologies that enable biologists to systematically investigate the expression of genes along with spatial information. Upon data acquisition, one major hurdle is the subsequent interpretation and visualization of the datasets acquired. To address this challenge, is presented, which is a novel data visualization system with interactive functionalities designed to help biologists interpret spatially resolved transcriptomic datasets. By implementing the system in two separate immersive environments, fish tank virtual reality (FTVR) and head-mounted display virtual reality (HMD-VR), biologists can interact with the data in novel ways not previously possible, such as visually exploring the gene expression patterns of an organ, and comparing genes based on their 3D expression profiles. Further, a biologist-driven use-case is presented, in which immersive environments facilitate biologists to explore and compare the heart expression profiles of different genes.
Keywords:
Spatially-resolved transcriptomics
Spatial transcriptomics
Virtual reality
Fish tank virtual reality
Head-mounted display
Immersive analytics
Immersive environment
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Journal

Visual Computing for Industry Biomedicine and Art cover
Visual Computing for Industry Biomedicine and Art
IF:
6
Papers:
178
Citations:
702

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U
University of Konstanz
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