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SPDYE3 promotes cell cycle and LUSC progression by regulating the CDC25C/CDK1 pathway
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王
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DOI：10.1016/j.biocel.2025.106825.png)
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Abstract
En 中文
Lung cancer is the primary reason for global cancer-related deaths. Targeted therapy is currently absent for lung squamous cell carcinoma (LUSC), a significant pathological subtype of lung cancer. The gene SPDYE3, a member of the Speedy/Ringo gene family, is highly expressed in different cancer tissues and functions as a cell cycle regulator. However, the potential mechanisms and clinical significance of SPDYE3 in LUSC remain unknown.
Keywords:
Lung squamous cell carcinoma
SPDYE3
Cell cycle
CDK1
CDC25C
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