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Specific reversal agents for direct oral anticoagulants in neurosurgical emergencies – a systematic review
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DOI:10.1016/j.rpth.2025.103225.png)
Abstract
En 中文
Direct oral anticoagulants (DOACs) are widely used but pose significant challenges in emergency neurosurgical settings. Idarucizumab and andexanet alfa are approved reversal agents, yet their effectiveness and safety in neurosurgical emergencies remain unclear. This systematic review evaluates the current evidence on DOAC reversal in patients undergoing emergency neurosurgical interventions.
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