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Spherical Nucleic Acids

delete2012-01-09
delete1.1K
PRE
AI
J
Joshua I. Cutler
E
Evelyn Auyeung
C
Chad A. Mirkin *
DOI:10.1021/ja209351udelete
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Abstract

Abstract

En 中文
A historical perspective of the development of spherical nucleic acid (SNA) conjugates and other three-dimensional nucleic acid nanostructures is provided. This Perspective details the synthetic methods for preparing them, followed by a discussion of their unique properties and theoretical and experimental models for understanding them. Important examples of technological advances made possible by their fundamental properties spanning the fields of chemistry, molecular diagnostics, gene regulation, medicine, and materials science are also presented.
Keywords:
MODIFIED GOLD-NANOPARTICLE
COLORIMETRIC DETECTION
ASYMMETRIC FUNCTIONALIZATION
STRUCTURAL-CHARACTERIZATION
SCAVENGER RECEPTORS
OPTICAL-PROPERTIES
PARTICLE-SIZE
DNA DETECTION
CAGED DIMERS
NANO-FLARES

Journal

Journal of the American Chemical Society cover
Journal of the American Chemical Society
IF:
15.6
Papers:
20.0W
Citations:
60.2W

Organization

N
northwestern university
Scholars:
1.1K
Papers: 409
Citations: 0
Cited Papers

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