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Stability of the translocator protein 18 kDa density within cognitive circuits in brains of virally-suppressed people with HIV
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DOI：10.1097/QAD.0000000000004416.png)
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Abstract
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[C-11]DPA-713 positron emission tomography (PET) has shown higher translocator protein (TSPO) availability, a marker of glial response, in cognitive control and declarative memory brain regions of virally suppressed people with HIV (VS-PWH). Here, 14 VS-PWH completed repeat TSPO PET after similar to 18 months. Regional TSPO was largely time-stable, with modest variability in some participants that was unrelated to antiretroviral therapy. Further study of a stable, higher TSPO density in select brain regions of VS-PWH is warranted.
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