Steroids in Organ Transplantation: Immunosuppression and Tolerance

null Jyoti

doi:10.1016/j.jsbmb.2026.107039

Steroids in Organ Transplantation: Immunosuppression and Tolerance

2026-05-21

0

PRE

AI

N

null Jyoti

G

Gurpreet Singh

M

Mamta Bishnoi

R

Ramandeep Kaur

S

Surjeet Kaur Sethi

N

null Hemlata

D

Deepika Paliwal

R

Richa Minhas

M

Mothukuri Bhanu Akash

H

Harmandeep Kaur Gulati *

DOI：10.1016/j.jsbmb.2026.107039

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Abstract

En 中文

• The role of receptor interaction, gene regulation, and the modulation of inflammatory responses in regulation of glucocorticoid activity. • Their clinical importance is investigated for each stage of transplant therapy: induction, long-term maintenance, and acute rejection. • Steroids drive immune tolerance, particularly by encouraging regulatory T cells, which balance the immune system.

Keywords:

Glucocorticoid activity

Immune tolerance

Regulatory T cells

Organ transplantation

Inflammatory responses

Steroids in Organ Transplantation: Immunosuppression and Tolerance

Abstract

Journal

Organization