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STING deficiency does not rescue short telomere-mediated aging phenotypes and longevity in TERC- or TERT-telomerase deficient mice

delete2026-08-06
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OA
AI
R
Rosa M. Marión
J
José Carlos González
J
Juana M. Flores
E
Elena Piñeiro-Yáñez
R
Rosa Serrano
M
Marı́a A. Blasco *
DOI:10.1016/j.celrep.2026.117786delete
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Abstract

Abstract

En 中文
• STING pathway is not activated in telomerase-deficient mice with short telomeres • p53 activation in telomerase-deficient mice with short telomeres is STING independent • STING does not mediate aging phenotypes associated with short telomeres in mice
Keywords:
telomeres
telomerase
aging
inflammation
stimulator of interferon genes
STING
CP: molecular biology
CP: immunology

Journal

Cell Reports cover
Cell Reports
IF:
6.9
Papers:
1.7W
Citations:
10.2W

Organization

S
spanish national cancer centre
Scholars:
2
Papers: 1
Citations: 0
S
spanish national research cancer centre
Scholars:
5
Papers: 1
Citations: 0
C
complutense university of madrid
Scholars:
1.9K
Papers: 975
Citations: 0
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