Return
STING deficiency does not rescue short telomere-mediated aging phenotypes and longevity in TERC- or TERT-telomerase deficient mice
R
J
J
E
R
M
DOI:10.1016/j.celrep.2026.117786.png)
Abstract
En 中文
• STING pathway is not activated in telomerase-deficient mice with short telomeres • p53 activation in telomerase-deficient mice with short telomeres is STING independent • STING does not mediate aging phenotypes associated with short telomeres in mice
Keywords:
telomeres
telomerase
aging
inflammation
stimulator of interferon genes
STING
CP: molecular biology
CP: immunology
Journal
IF:
6.9
Papers:
1.7W
Citations:
10.2W
