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Strain Dependent Diffusivities of Glucose and Lactate in the Human Temporomandibular Joint Disc

delete2026-06-18
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PRE
AI
M
Marshall B. Wilson
D
Dustin Mueller
E
Elliott Moore
A
Alex Long
F
Farhad Ahmadi
S
Shuchun Sun
B
Brooke Damon
C
Cherice Hill
P
Peng Chen
Y
Yongren Wu
H
Hai Yao *
DOI：10.1016/j.jmbbm.2026.107511delete
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Abstract

Abstract

En 中文
• Compressive strain significantly reduces glucose and lactate diffusivity in human TMJ discs. • Strain-induced decreases in porosity strongly correlate with impaired solute transport. • Sustained loading simulations predict localized nutrient depletion and reduced ATP synthesis. • Human TMJ discs exhibit species-specific strain–diffusion behavior compared to porcine models.

Journal

Journal of the Mechanical Behavior of Biomedical Materials cover
Journal of the Mechanical Behavior of Biomedical Materials
IF:
3.5
Papers:
6.7K
Citations:
2.1W

Organization

U
University of Rochester
Scholars:
2.6W
Papers: 2.1W
Citations: 2.2W
M
medical university of south carolina
Scholars:
2.0K
Papers: 766
Citations: 0
C
Clemson University
Scholars:
1.3W
Papers: 1.1W
Citations: 1.4W
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