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Structural basis for TrbM-enhanced conjugation and interbacterial killing in the RP4 plasmid
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DOI：10.1016/j.isci.2026.116436.png)
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Abstract
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• TrbM from RP4 resembles conjugative bacterial adhesins • TrbM homologs from R751, R388, and pKM101 can complement Δ RP4-trbM mutants • R6K TivB12 does not restore RP4 conjugation or killing • The predicted TrbM domain remains functional after repositioning inside homologs
Keywords:
Medical microbiology
Biological sciences
Biochemistry
Bacteriology
Molecular microbiology
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