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Structural Biology outside the box - inside the cell
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DOI：10.1016/j.sbi.2017.06.007.png)
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Abstract
En 中文
Recent developments in cellular cryo-electron tomography, in-cell single-molecule Forster resonance energy transfer spectroscopy, nuclear magnetic resonance-spectroscopy and electron paramagnetic resonance-spectroscopy delivered unprecedented insights into the inner workings of cells. Here, we review complementary aspects of these methods and provide an outlook toward joint applications in the future.
Keywords:
NUCLEAR-PORE COMPLEX
SINGLE-MOLECULE SPECTROSCOPY
EPR DISTANCE MEASUREMENTS
CRYOELECTRON TOMOGRAPHY
NMR-SPECTROSCOPY
PROTEIN STABILITY
LIVING CELLS
CRYO-EM
DYNAMICS
FLUORESCENCE
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