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Structured illumination diffraction phase microscopy for broadband, subdiffraction resolution, quantitative phase imaging

delete2014-02-12
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S
Shwetadwip Chowdhury *
J
Joseph A. Izatt
DOI:10.1364/OL.39.001015delete
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Abstract

Abstract

En 中文
Structured illumination microscopy (SIM) is an established technique that allows subdiffraction resolution imaging by heterodyning high sample frequencies into the system's passband via structured illumination. However, until now, SIM has been typically used to achieve subdiffraction resolution for intensity-based imaging. Here, we present a novel optical setup that uses structured illumination with a broadband light source to obtain noise-reduced, subdiffraction resolution, quantitative phase imaging (QPM) of cells. We compare this with a previous work for subdiffraction QPM imaging via SIM that used a laser source, and was thus still corrupted by coherent noise. (C) 2014 Optical Society of America
Keywords:
DIGITAL HOLOGRAPHIC MICROSCOPY
FLUORESCENCE MICROSCOPY
LIMIT
SUPERRESOLUTION
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Journal

Optics Letters cover
Optics Letters
IF:
3.3
Papers:
4.0W
Citations:
7.6W

Organization

D
Duke University
Scholars:
6.3W
Papers: 5.7W
Citations: 6.5W
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