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Superficial parasternal intercostal plane block with ropivacaine versus placebo for opioid exposure after cardiac surgery (EPOCH CardioLink-10): a multicentre, double-blind, randomised trial
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DOI：10.1016/j.lana.2026.101508.png)
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Abstract
En 中文
Cardiac surgery performed through a midline chest incision (median sternotomy) is associated with substantial postoperative pain and opioid use, the latter of which remains the dominant modality of analgesia. Contemporary international guidelines prioritise opioid-sparing, multimodal strategies; however, robust randomised evidence to support specific opioid-sparing analgesic approaches in cardiac surgery is lacking.
Keywords:
Perioperative pain management
Cardiac surgery
Opioid consumption superficial parasternal intercostal plane block
SPIP block
Median sternotomy
Postoperative pain
Opioid-sparing analgesia
Ropivacaine
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