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Superior drug retention of selective JAK1 inhibitors compared to pan-JAK inhibitors in rheumatoid arthritis: A meta-analysis of real-world evidence

delete2026-04-21
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PRE
AI
Y
Young Ho Lee *
G
Gwan Gyu Song
DOI：10.1016/j.semarthrit.2026.152989delete
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Abstract

Abstract

En 中文
The durability of Janus kinase (JAK) inhibitors in routine clinical practice is still debated. This study aimed to compare the drug retention rates of selective JAK1 inhibitors (upadacitinib, filgotinib) with pan-JAK inhibitors (tofacitinib, baricitinib) in patients with rheumatoid arthritis (RA) using real-world data.
Keywords:
JAK inhibitors
JAK1 inhibitors
pan-JAK inhibitors
rheumatoid arthritis
drug retention

Journal

Seminars in Arthritis and Rheumatism cover
Seminars in Arthritis and Rheumatism
IF:
4.4
Papers:
423
Citations:
1.0W

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