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Sustained Activity Encoding Working Memories: Not Fully Distributed
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DOI：10.1016/j.tins.2017.04.004.png)
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Abstract
En 中文
Working memory (WM) is the ability to remember and manipulate information for short time intervals. Recent studies have proposed that sustained firing encoding the contents of WM is ubiquitous across cortical neurons. We review here the collective evidence supporting this claim. A variety of studies report that neurons in prefrontal, parietal, and inferotemporal association cortices show robust sustained activity encoding the location and features of memoranda during WM tasks. However, reports of WM-related sustained activity in early sensory areas are rare, and typically lack stimulus specificity. We propose that robust sustained activity that can support WM coding arises as a property of association cortices downstream from the early stages of sensory processing.
Keywords:
SHORT-TERM-MEMORY
INFERIOR TEMPORAL CORTEX
AUDITORY RECOGNITION MEMORY
VENTRAL PREFRONTAL CORTEX
SUPPLEMENTARY EYE FIELD
ONE SENSORY MODALITY
NEURONAL-ACTIVITY
UNIT-ACTIVITY
NEURAL ACTIVITY
PARIETAL CORTEX
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