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Synaptic model for spontaneous activity in developing networks
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DOI：10.1016/j.neucom.2004.10.074.png)
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Abstract
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Spontaneous rhythmic activity occurs in many developing neural networks. The activity in these hyperexcitable networks is comprised of recurring episodes consisting of cycles of high activity that alternate with silent phases with little or no activity. We introduce a new model of synaptic dynamics that takes into account that only a fraction of the vesicles stored in a synaptic terminal is readily available for release. We show that our model can reproduce spontaneous rhythmic activity with the same general features as observed in experiments, including a positive correlation between episode length and length of the preceding silent phase. (c) 2004 Elsevier B.V. All rights reserved.
Keywords:
synapse model
hyperexcitable network
synaptic vesicle pools
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