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Syntabulin promotes heart failure by enhancing SR–mitochondria tethering and impairing mitofission

delete2026-06-29
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PRE
AI
Y
Ying Li
Z
Ziquan Sun
H
Haixia Duan
M
Mingyue Wu
J
Jing Yi
G
Gang Wang
W
Wenjuan Liu
C
Chenglin Zhang
W
Wanwen Cheng
J
Jicheng Li
W
Weixuan Chen
K
Kunfu Ouyang
H
Hui Tan
Y
Yueheng Wu *
J
Jie Liu *
DOI：10.1093/cvr/cvag139delete
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Abstract

Abstract

En 中文
Mitochondrial dysfunction is a critical driver of heart failure (HF). Syntabulin (SYBU), known for its role as a motor linker at the outer mitochondrial membrane in neuronal system, has recently been suggested as a heart failure-associated gene. However, the role of SYBU in regulating cardiac function remains unclear.

Journal

Cardiovascular Research cover
Cardiovascular Research
IF:
13.3
Papers:
1.2W
Citations:
2.8W

Organization

S
Shenzhen University Medical School
Scholars:
140
Papers: 45
Citations: 0
S
Shenzhen Children's Hospital
Scholars:
123
Papers: 62
Citations: 1.2K
P
Peking University Shenzhen Hospital
Scholars:
693
Papers: 217
Citations: 4.1K
G
Guangdong Provincial People's Hospital
Scholars:
525
Papers: 137
Citations: 7.3K
Cited Papers

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