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Systemic infections alter cortical transcriptional signatures in Alzheimer’s disease
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DOI：10.1016/j.neurobiolaging.2026.06.010.png)
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Abstract
En 中文
• 57 unique differentially expressed genes in AD brain during systemic infection. • Systemic infection shifts immune related pathway activity in the AD brain. • Gene co-expression modules were associated with AD and systemic infection.
Keywords:
Alzheimer’s disease (AD)
Brain
Systemic infection
Inflammation
Transcriptomics
RNA sequencing
Weighted gene correlation network analysis (WGCNA)
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