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Systemic therapy, gastrectomy, cytoreductive surgery, and hyperthermic intraperitoneal chemotherapy versus systemic therapy alone for gastric cancer with limited peritoneal metastases (PERISCOPE II): final results of a multicentre, randomised, controlled, phase 3 trial after an unplanned commissioned interim analysis

delete2026-07-08
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PRE
AI
J
Judith S E Quik
M
Marieke A Vollebergh
V
Valesca P Retèl
K
Karen van der Sluis
W
Willem J Koemans
R
Rosa T van der Kaaij
M
Madelon M Voets
M
Misha D P Luyer
I
Irene E G van Hellemond
B
Bas P L Wijnhoven
B
Bianca Mostert
R
Richard van Hillegersberg
N
Nadia Haj Mohammad
B
Boudewijn van Etten
D
Derk J de Groot
O
Olli Helminen
J
Jakob Hedberg
P
Peter H Cashin
J
Julie L Harbjerg
A
Alexander A F A Veenhof
DOI:10.1016/S1470-2045(26)00144-0delete
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Abstract

Abstract

En 中文
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) is widely used for patients with gastric cancer and peritoneal metastases. However, the efficacy of this treatment has never been compared with that of systemic therapy. We aimed to investigate the efficacy of gastrectomy with cytoreductive surgery and HIPEC for patients with gastric cancer and limited peritoneal metastases, compared with systemic therapy alone.

Journal

T
The Lancet Oncology
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Papers:
348
Citations:
1

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