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Targeted Transcriptomic Profiling Identifies Biomarkers and Molecular Features Associated With Immunotherapy Response in Classic Hodgkin Lymphoma

delete2026-08-05
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PRE
AI
L
Leticia Hamana
M
Mario L. Marques-Piubelli
L
Lu Wei
K
Khaja Khan
L
Lakshmi Kakarala
L
Li Shen
I
Ignacio I. Wistuba
H
Hun Ju Lee
L
Luisa M. Solis
F
Francisco Vega *
DOI:10.1016/j.modpat.2026.101060delete
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Abstract

Abstract

En 中文
Classic Hodgkin lymphoma (CHL) is a highly curable disease. However, a subset of patients develops relapsed/refractory disease, underscoring the need for predictors of treatment response. Although immune-checkpoint inhibitors have improved outcomes, many patients still experience suboptimal responses. A deeper understanding of the CHL transcriptomic landscape may improve patient stratification and guide treatment approaches.

Journal

Modern Pathology cover
Modern Pathology
IF:
5.5
Papers:
5.2K
Citations:
1.8W

Organization

M
md anderson cancer center
Scholars:
227
Papers: 102
Citations: 1
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