.png){kind=icon}
.png){kind=icon}
Return
Targeting the NLRP3 Inflammasome in Alzheimer’s Disease: Mechanistic Insights and Therapeutic Advances
.png){kind=icon}
PRE
AI
W
F
Z
C
Y
J
J
W
DOI：10.1016/j.arr.2026.103273.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
• This review elucidates the research advancement on NLRP3 inflammasome from the aspect of structure, function and activation signaling. • It uncovers the inextricable role of NLRP3 inflammasome in AD pathogenesis from the preclinical and clinical evidence. • It highlights the capacities of different glia, cellular processes and signaling events that regulate the Aβ-induced NLRP3 inflammasome activation. • It overviews the existing anti-AD agents that inhibit the NLRP3 inflammasome activation.
Journal
IF:
12.4
Papers:
3.5K
Citations:
2.3W
Organization
Cited Papers