1
Return

TCM-Driven Circadian Modulation in Cancer: Engineering Spatiotemporal Drug Delivery for Precision Oncology

delete2026-08-06
delete0
delete
OA
AI
Z
Zhengguang Zhang
Y
Yuanchao Feng
W
Wenjia Zhang
Z
Ziming Mu
F
Fuqiong Zhou
DOI：10.2147/ijn.s613697delete
deleteOriginal
deleteOriginal request for help
deleteShare
deleteSave
Abstract

Abstract

En 中文
Circadian disruption constitutes a hallmark of cancer, driving tumorigenesis, progression, and therapy resistance via dysregulation of core clock genes. Emerging evidence indicates that traditional Chinese medicine (TCM), primarily through Chinese herbal medicine (CHM), exerts promising chronotherapeutic effects by modulating tumor-intrinsic circadian rhythms. Bioactive CHM constituents restore the oscillatory expression of clock genes (eg,
Keywords:
circadian modulation
Chinese herbal medicine
spatiotemporal drug delivery
modernization of traditional Chinese medicine

Journal

International Journal of Nanomedicine cover
International Journal of Nanomedicine
IF:
6.5
Papers:
8.5K
Citations:
4.2W

Organization

S
school of medicine
Scholars:
3.5K
Papers: 1.2K
Citations: 0
C
central laboratory
Scholars:
366
Papers: 165
Citations: 0
Cited Papers

Cited Papers

Citing Papers

Citing Papers