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Techniques To Control Polymersome Size

delete2015-10-12
delete152
PRE
AI
R
Regina Bleul
R
Raphael Thiermann
M
Michael Maskos *
DOI:10.1021/acs.macromol.5b01500delete
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Abstract

Abstract

En 中文
Polymersomes as synthetic analogues of liposomes appear frequently in relevant literature as promising candidates for a wide range of different applications including drug delivery, theranostic multitools, and nanoreactors. In particular, as nanotransporters for nanomedical applications in vivo, requirements concerning the reproducible manufacturing and reliable size control are extremely high. This Perspective highlights the importance of size control especially in the context of nanomedicine and gives an overview of the theoretical background of amphiphilic self-assembly leading to different preparation methods, where their feasibility of controlling polymersomes' size is discussed.
Keywords:
BLOCK-COPOLYMER VESICLES
MOLECULAR-DYNAMICS SIMULATION
INFRARED-EMISSIVE POLYMERSOMES
TRIBLOCK COPOLYMER
BIODEGRADABLE POLYMERSOMES
MULTIPLE MORPHOLOGIES
DIBLOCK COPOLYMERS
TERNARY-SYSTEM
IN-VIVO
SOLVENT
AI Summary

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Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.

Journal

Macromolecules cover
Macromolecules
IF:
5.2
Papers:
3.7W
Citations:
9.4W

Organization

I
institut fur mikrotechnik mainz gmbh (imm)
Scholars:
213
Papers: 156
Citations: 0