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Terpenoids in Euphorbia milii Ch. des Moulins and their anti-rheumatic potential

delete2026-05-06
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PRE
AI
H
Hong Yi Su
M
Meng Yi Deng
X
Xin Wang
H
Huang Shuai
L
Lin Chen *
X
Xian Li Zhou *
DOI：10.1016/j.phytochem.2026.114947delete
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Abstract

Abstract

En 中文
• Seven undescribed and sixteen known terpenoids were isolated from Euphorbia milii. • Their structures and absolute configurations were elucidated by NMR, MS, X-ray diffraction, and NMR calculations. • Compound 3 belonged to a rare 6/12-fused taxane-type diterpenoid. • Compound 2 and 20 exhibited anti-rheumatic activity in vitro bioactivity assays. • Preliminary studies indicated that compound 2 could promote MH7A cell apoptosis.
Keywords:
Terpenoids
Euphorbia milii
Diterpenoid
Anti-rheumatic activity
Apoptosis

Journal

Phytochemistry cover
Phytochemistry
IF:
3.4
Papers:
1.3W
Citations:
3.2W

Organization

S
southwest jiaotong university
Scholars:
7.6K
Papers: 2.7K
Citations: 0
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