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TFOS DEWS III: Digest

delete2025-06-04
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OA
AI
F
Fiona Stapleton *
P
Pablo Argüeso
P
Penny A. Asbell
D
Dimitri T. Azar
C
Charles Bosworth
W
Wei Chen
J
Joseph B. Ciolino
J
Jennifer P. Craig
J
Juana Gallar
A
Anat Galor
J
José Álvaro Pereira Gomes
I
Isabelle Jalbert
Y
Ying Jie
L
Lyndon Jones
K
Kenji Konomi
Y
Yang Liu
J
Jesús Merayo‐Lloves
F
Fabíola Reis de Oliveira
V
Victor L. Perez
E
Eduardo Melani Rocha
B
Benjamin D. Sullivan
D
David A. Sullivan
J
Jelle Vehof
S
Susan Vitale
M
Mark Willcox
J
James S. Wolffsohn
M
Murat Doğru
DOI:10.1016/j.ajo.2025.05.040delete
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Abstract

Abstract

En 中文
This digest summarizes the interdisciplinary research in dry eye disease (DED) published since the 2017 TFOS DEWS II reports. It comprises 7 topics including Sex, Gender, and Hormones; Epidemiology; Pathophysiology; Tear Film; Pain and Sensation; Iatrogenic Dry Eye; and Clinical Trial Design and explores how each of these inform diagnostic methodology, disease subtype, and management of DED.
Keywords:
ADDE
Aqueous-deficient dry eye
BALB/c
BALB/C wildtype (mice)
CI
confidence interval
CXL
Corneal cross-linking
DED
Dry eye disease
DEQ-5
5-Item Dry Eye Questionnaire
DEWS
Dry Eye Workshops
DNA
Deoxyribonucleic acid
EDE
Evaporative dry eye
FDA
Food and drug administration
(f)MRI
(Functional) magnetic resonance imaging
GVHD
Graft-versus-host disease
HLA
Human leukocyte antigen
HPMC
Hydroxypropyl methylcellulose
ICAM-1
Intercellular Adhesion Molecule 1
IL
Interleukin
IGF
Insulin-like growth factor
IVCM
In vivo confocal microscopy
LASIK
Laser-assisted in situ keratomileusis
LIPCOF
Lid-parallel conjunctival folds
LLT
Lipid layer thickness
MGD
Meibomian gland dysfunction
MGYLS
Meibomian glands yielding liquid secretion
MMP
Matrix metalloproteinase
MUC4
Mucin 4
NGF
Nerve growth factor
NIBUT
Non-invasive tear film breakup time
NF-kB
Nuclear factor kappa-light-chain-enhancer of activated B cells
NRS
Numerical rating scale
OCT
Optical coherence tomography
OR
Odds ratio
OSDI
Ocular Surface Disease Index
PRK
Photorefractive keratectomy
QoL
Quality of Life
SANDE
Symptom Assessment iN Dry Eye questionnaire
SPEED
Standard Patient Evaluation of Eye Dryness questionnaire
TBUT
Tear film breakup time
TED
Thyroid eye disease
TFOS
Tear Film & Ocular Surface Society
TRPM8
Transient Receptor Potential cation channel subfamily M member 8
VAS
Visual analogue scale
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Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.

Journal

American Journal of Ophthalmology cover
American Journal of Ophthalmology
IF:
4.2
Papers:
3.0W
Citations:
2.8W

Organization

N
national eye clinic research center
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Citations: 0
T
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C
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A
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F
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Papers: 135
Citations: 0
U
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Citations: 9
U
University of Miami Miller School of Medicine
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T
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Citations: 0
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U
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Papers: 2.5W
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A
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Scholars:
1
Papers: 1
Citations: 0
T
tear film and ocular surface society
Scholars:
1
Papers: 1
Citations: 0
U
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Scholars:
362
Papers: 130
Citations: 7.9W
T
The University of Auckland
Scholars:
564
Papers: 286
Citations: 3
U
University of Waterloo
Scholars:
2.2W
Papers: 2.3W
Citations: 3.3W
H
Harvard Medical School
Scholars:
6.5W
Papers: 4.8W
Citations: 91
Universidad de Oviedo cover
Universidad de Oviedo
Scholars:
461
Papers: 186
Citations: 1.0W
Z
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Papers: 376
Citations: 1
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