TGFβ signaling is required during human and chick Neural Crest formation

Gustavo A. Gomez

doi:10.1016/j.ydbio.2026.04.018

TGFβ signaling is required during human and chick Neural Crest formation

2026-05-07

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AI

G

Gustavo A. Gomez

B

Bhaval Parmar

M

Man Wong

J

Jacqueline C. Hernandez

I

Iris Paula Guimarães-Andrade

M

Martín I. García‐Castro *

DOI：10.1016/j.ydbio.2026.04.018

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Abstract

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• The TGFβ signaling pathway plays a critical role in neural crest formation. • Neural crest formation from human embryonic stem cells and in chick embryos require TGFβ signaling. • An optimal mid-level dose of TGFβ is necessary for cranial neural crest formation.

Keywords:

TGFβ signaling

neural crest formation

human embryonic stem cells

chick embryos

cranial neural crest

TGFβ signaling is required during human and chick Neural Crest formation

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