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The actin crosslinker Fimbrin is required for force sensing at tricellular junctions
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DOI：10.1016/j.devcel.2026.07.001.png)
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Abstract
En 中文
• Fimbrin is recruited to epithelial tricellular junctions in response to force • Fimbrin remodels actin and enhances actomyosin contractility under tension • Fimbrin directs the localization of multiple proteins that reinforce cell adhesion • Plastin3 and Afadin localize to tricellular junctions under force in mouse epithelia
Keywords:
Mechanotransduction
epithelial morphogenesis
actin cytoskeleton
cell adhesion
myosin
Fimbrin
actin crosslinker
Drosophila
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