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The astrocytic connectome: Gap-Junction topology beyond diffuse syncytium

delete2026-06-12
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PRE
AI
J
Jia-Qi Zhang
W
Wei Sun *
W
Weilin Jin *
DOI:10.1016/j.tcb.2026.05.005delete
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Abstract

Abstract

En 中文
Whether astrocytes form selective long-range networks remains unresolved. Cooper et al. use connexin 43-TurboID to reveal region-specific, plastic astrocyte gap-junction networks that partly overlap yet are not reducible to canonical neuronal projections. We discuss how this work refines the concept of astrocyte syncytial coupling and expands models of inter-regional brain connectivity.

Journal

Trends in Cell Biology cover
Trends in Cell Biology
IF:
18.1
Papers:
3.1K
Citations:
2.0W

Organization

S
shanghai jiao tong university
Scholars:
15.1W
Papers: 11.5W
Citations: 159
F
fudan university
Scholars:
11.3W
Papers: 7.6W
Citations: 121
L
Lanzhou University
Scholars:
9.9K
Papers: 2.8K
Citations: 3.8W
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