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The benefit of deep genomic testing for asymptomatic high-risk individuals undergoing surveillance for pancreatic adenocarcinoma: European registry for hereditary pancreatic diseases (EUROPAC-PLUS)
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DOI：10.1016/j.neo.2026.101316.png)
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Abstract
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• High Risk Individuals (HRI) should undergo risk-stratified surveillance for PDAC. • Most HRI are ineligible for genetic testing, denying entrance into surveillance. • Extended germline testing can find unknown pathogenic variants which reverses this.
Keywords:
Pancreatic ductal adenocarcinoma
High risk individuals
Surveillance
Germline genetic testing
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