.png){kind=icon}
Return
The decrease in breast-cancer incidence in 2003 in the United States.
.png){kind=icon}
OA
AI
DOI：10.1056/NEJMsr070105.png)
.png){kind=icon}
.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
An initial analysis of data from the National Cancer Institute's Surveillance, Epidemiology, and End Results ( SEER) registries shows that the age-adjusted incidence rate of breast cancer in women in the United States fell sharply ( by 6.7%) in 2003, as compared with the rate in 2002. Data from 2004 showed a leveling off relative to the 2003 rate, with little additional decrease. Regression analysis showed that the decrease began in mid-2002 and had begun to level off by mid-2003. A comparison of incidence rates in 2001 with those in 2004 ( omitting the years in which the incidence was changing) showed that the decrease in annual age-adjusted incidence was 8.6% (95% confidence interval [CI], 6.8 to 10.4). The decrease was evident only in women who were 50 years of age or older and was more evident in cancers that were estrogen-receptor - positive than in those that were estrogen-receptor - negative. The decrease in breast-cancer incidence seems to be temporally related to the first report of the Women's Health Initiative and the ensuing drop in the use of hormone-replacement therapy among postmenopausal women in the United States. The contributions of other causes to the change in incidence seem less likely to have played a major role but have not been excluded.
Keywords:
HORMONE REPLACEMENT THERAPY
AI Summary
Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.
Journal
IF:
78.5
Papers:
2.7W
Citations:
39.7W
Organization
No organization information available
Cited Papers
ShareSaveEffects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival:: an overview of the randomised trials.png)
LANCET
LANCETIF88.5
PREAI
ShareSaveBreast cancer and hormone replacement therapy: collaborative reanalysis of data from 51 epidemiological studies of 52,705 women with breast cancer and 108,411 women without breast cancerLANCETOAAI
LANCETIF88.5
OAAIShareSaveInvestigation of the2p3∕2−3d5∕2line emission ofAu53+–Au69+for diagnosing high energy density plasmas
PREAI
ShareSaveShareSaveShareSave
View more