The impact of global recruitment and country income on placebo rates in inflammatory bowel disease clinical trials

Shane W Goodwin

doi:10.1093/ecco-jcc/jjag081

The impact of global recruitment and country income on placebo rates in inflammatory bowel disease clinical trials

2026-06-25

0

OA

AI

S

Shane W Goodwin

Y

Yuhong Yuan

S

Siddharth Singh

V

Virginia Solitano

V

Vineet Ahuja

S

Sudheer Kumar Vuyyuru

N

Neeraj Narula

C

Christopher Ma

V

Vipul Jairath

DOI：10.1093/ecco-jcc/jjag081

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Abstract

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Despite progress in understanding placebo effects in clinical trials of inflammatory bowel disease (IBD), there is a limited understanding of how socioeconomic factors of recruiting countries impact placebo rates. We investigated the association of socioeconomic factors across recruitment sites on placebo rates in IBD randomized controlled trials.

The impact of global recruitment and country income on placebo rates in inflammatory bowel disease clinical trials

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