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The impact of sex hormones and sex chromosomes on the HDL anti-inflammatory capacity in transgender individuals
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DOI：10.1016/j.jlr.2026.101076.png)
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Abstract
En 中文
Interest in the cardiovascular disease (CVD) field is shifting from high-density lipoprotein cholesterol (HDL-C) levels to exploring function of HDL particles. Among these, anti-inflammatory properties of HDL emerged as key metric associated with protection against incident CVD events, notably in a highly sexually dimorphic manner. Therefore, the present study investigated the impact of sex hormones and sex chromosomes on the HDL anti-inflammatory activity.
Keywords:
HDL
HDL anti-inflammatory capacity
inflammation
CVD
HDL function
HDL subspecies
lipidome
transgender
sex hormones
sex chromosomes
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