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The octameric shift in plant immune signaling
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DOI：10.1016/j.tcb.2026.06.007.png)
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Abstract
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Nucleotide-binding leucine-rich repeat (NLR) receptors are ubiquitous intracellular sensors. Guo et al . recently revealed that the wheat CCG10-NLR, Wheat Autoimmunity 3, forms a previously undescribed plant octameric resistosome to mediate cell death and immunity. This discovery uncovers a distinct configuration, highlighting the remarkable structural plasticity in plant immune signaling.
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